Mice
Mice are the most common rodent pest in the United States, with the house mouse being found in virtually every state and community. They are small, adaptable, and capable of squeezing through gaps as small as a quarter inch - roughly the diameter of a pencil. A single pair of mice can produce up to 60 offspring per year, and populations in structures can grow from a few individuals to hundreds in months. Deer mice are the primary mouse species in rural and semi-rural areas and are the primary reservoir for hantavirus in North America.
Species in This Group (4)

House Mouse
Mus musculus
The House Mouse is the most common commensal rodent in the world and the leading mammalian pest of homes and commercial buildings.

Deer Mouse
Peromyscus maniculatus
The Deer Mouse is the most abundant mammal in North America and the primary reservoir of Sin Nombre hantavirus, which causes hantavirus pulmonary syndrome (HPS), a potentially fatal respiratory disease.

White-Footed Mouse
Peromyscus leucopus
The White-Footed Mouse is the most important reservoir host for the Lyme disease spirochete in the eastern United States, infecting larval blacklegged ticks that later transmit the disease to humans.

Roof Mouse
Mus musculus domesticus
The Roof Mouse is the western subspecies of the common house mouse, prevalent in warmer regions of the Americas, southern Europe, and other temperate to subtropical areas.
Key Behaviors
House mice are curious and exploratory, quickly investigating new objects in their environment, which makes them easier to trap than rats. They establish small home ranges of 10 to 30 feet and produce 40 to 100 droppings per day. They can survive with very little water, obtaining moisture from their food. They nest in insulation, paper, fabric, and other soft materials in wall voids, attics, and appliance housings. Deer mice prefer outdoor nesting but readily enter structures in fall.
Risks & Concerns
Mice contaminate food and surfaces with urine, feces, and hair. They trigger allergies and asthma, particularly in children in urban housing. Deer mice transmit hantavirus, which causes hantavirus pulmonary syndrome with a 30 to 40 percent fatality rate. House mice gnaw on wiring, creating fire hazards, and damage insulation, packaging, and stored goods. Their small size and extreme agility make exclusion challenging - every gap of a quarter inch or larger must be sealed.
Quick Comparison
| Species | Size | Color | Key Trait |
|---|---|---|---|
| House Mouse | 65-95 mm body length, plus 60-100 mm tail; 12-30 g | Light brown to gray with a lighter underside | Small, slender body with large rounded ears, a pointed snout, and a nearly hairless tail about the same length as the body. Much smaller than rats, and can fit through gaps as small as 6 mm. |
| Deer Mouse | 70-100 mm body length, plus 50-120 mm tail; 15-32 g | Tawny brown to grayish-brown on top with a sharply contrasting white underside and white feet | Bicolored appearance with sharply defined brown upper body and white underside extending to the feet and the underside of the tail. Larger eyes and ears relative to body size than the house mouse. |
| White-Footed Mouse | 80-100 mm body length, plus 65-95 mm tail; 15-25 g | Reddish-brown to orange-brown on top with a white underside and white feet | Very similar to the deer mouse but typically has a slightly shorter, less distinctly bicolored tail. Critically, it is the primary reservoir host for the Lyme disease spirochete (Borrelia burgdorferi). |
| Roof Mouse | 65-95 mm body length, plus 60-100 mm tail; 12-28 g | Light grayish-brown to sandy-brown with a slightly lighter underside | A subspecies of the house mouse adapted to warmer climates. Tends to nest in upper portions of structures (attics, ceiling voids, upper cabinets) rather than at ground level, hence the common name. |
Need Help With Mice?
If you're seeing signs of mice in or around your home, professional treatment is the fastest way to stop the problem. Lotus Pest Control offers free inspections to identify the issue and recommend the right solution.